Are Ethnic Differences in Lung Function Explained by Chest Size

Standing height was the most important predictor of LF. Ethnic differences in lung function LF are recognised in adults and children.


Clinical Characterization And Possible Pathophysiological Causes Of The Deventilation Syndrome In Copd Scientific Reports

Differences in the length of UBS explained more of the ethnic differences in lung function than SH.

. The practice of using race or ethnicity in medicine to explain differences between individuals is being called into question because it may contribute to biased medical care and research that perpetuates health disparities and structural racism. 132 should be used for the major lung volumes to account for the ethnic differences between Africans and Europeans. PMC free article Google Scholar.

Despite recognised ethnic differences in lung function LF most reference ranges are based on white subjects and selection of appropriate equations is complicated by the increase in. Thorax Dec 2002 Vol 57 supplement III p41. Identification of the best linear measurements to explain.

Sorry we are unable to provide the full text but you may find it at the following locations. Other studies failed to justify ethnic differences in lung volumes by the variations in chest contours and suggest differences in inspiratory muscle strength andor lung compliance as alternative explanations. As a result forced vital capacity FVC and forced expiratory volume in one second FEV 1 are also larger.

Although differences in body proportions did not explain ethnic differences in lung function in our study this could be further examined in future studies possibly using more detailed chest and lung function measurements such as chest circumference sitting height or plethysmography. Social correlates had a smaller but significant impact. Future research needs to consider how differential development of lung capacity among ethnic minority children is compromised by the social patterning of growth trajectories.

Fetal Neonatal Ed Sep 2005. Observed differences in lung function between White and Black populations are often attributed to physiological differences in body proportions eg chest. Similar variation in sitting and standing height between aboriginal and white Australian children could have explained the observed differences in their venti- latory functions 4.

Are ethnic differences in lung function explained by chest size. A commonly cited example is the use of race or ethnicity in the interpretation of pulmonary function test PFT results yet the perspectives. Smaller scaling factors are proposed for other lung function indices.

The influence of chest dimensions on lung function was trivial. Differences in body habitus socio-economic and educational status nutrition and genetic ancestry 1-8 between ethnic groups are known to influence lung function results. Ethnicity was an independent predictor for all LF measures except PEF where the effect was marginal.

Whittaker AL Sutton AJ Beardsmore CS. Evidence that differences in chest dimensions in adults may contribute to ethnic differences in lung function20 A direct comparison of white Asian Indian and black children from the UK has demonstrated ethnic differences in lung function7 and we wanted to test the hypothesis that reduced lung function in Asian children. In Caucasians total lung capacity TLC is approximately 15-22 larger than in Chinese and Indians lJ.

9 The Global Lung Function Initiative GLI. It was hypothesised that differences in chest dimensions would explain differences in LF between Asian Indian and white schoolchildren. The current approach to interpretation of lung function measurements assumes that differences in lung function between racial and ethnic groups represent inherent and biological differences.

Ethnic minorities comprise 40 of the London population which may have considerable impact on healthcare provision. Despite long-standing attempts to identify factors underlying ethnic differences in lung function 1 3 4 the contribution of body physique is not well understood. Are ethnic differences in lung function explained by chest size.

Most prediction equations for LF are derived from whites so non-whites are at risk of erroneous assessment. There was no difference in alveolar distensibility or in the diffusion coefficient between the groups. Discussion Ethnic differences in lung function could be explained by a smaller ratio of sitting to standing height in blacks as compared to whites 16.

Ethnic differences in lung function have been well demonstrated between blacks of African descent and whites of European descent 2 3 5-12. Arch Dis Child Fetal Neonatal Ed. Standing height is a major determinant of lung function but differences in body proportions and composition may explain much of the remaining ethnic variation.

It is proposed that until further evidence is forthcoming for normal values a scaling factor of 1. The influence of chest dimensions on lung function was trivial. Differences in chest dimensions did not explain the substantial effect of ethnicity on LF.

Body mass index was smaller in Asians but did not explain differences in LF. Do variations in chest wall dimensions explain ethnicity-related differences in lung function. These findings suggest that Caucasians have larger lung volumes than Chinese and Indians because they have increased numbers of alveoli and physically larger chest cavities and not because of greater alveolar distensibility.

Current recommendations are to use ethnic-specific reference equations or a race correction factor for non-Caucasian individuals. Although differences in lung function are well documented between races the factors responsible are not established. Mechanisms whereby ethnicity exerts its influence may include differences in inspiratory muscle strength or lung compliance but.

FVC in whites was 134 bigger than in Asians of the same height and the FEV1 was 106 greater in whites. 2 Data from children and adolescents of AsiaPacific region showed a similar ethnic. This has been attributed at least in part to anthropometric differences between these ethnic groups with whites having larger chest volumes and shorter leg length ie larger trunk-to-leg ratio at a given height 4 9.

Ethnic differences in lung function in children and adolescents have been consistently reported and much of the difference has been explained by a difference in the proportion of the upper body segment in relation to total height in different ethnicities.


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